Imaging Mass Spectrometry
Mass spectrometry imaging (MSI) is a technique used to visualize the involves in distribution of molecules as biomarkers, metabolites, peptides or proteins by their molecular mass. Although widely used traditional methodologies like radiochemistry and immunohistochemistry achieve the same goal as MSI as they are limited abilities to analyze multiple samples at once. MSI considers as a qualitative method and signal generated through this technique is proportional to the relative of analyte of the compound.
Ionization Techniques of MSI:
Secondary Ion Mass Spectrometry Imaging
Laser Ablation Electrospray Ionization (LAESI)
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)