Proteomics is the large-scale study of proteins and proteomes.Proteins are vital parts of  functional living organisms, Proteomics  refers to the large-scale experimental protein purification and mass spectrometry analysis.Proteomic technologies is use for  identification and quantification of overall proteins present content of a cell, tissue or an organism.Mass spectrometry with LC–MS-MS and MALDI-TOF/TOF being widely used equipment is the central among current proteomics.Proteomics is also useful in disease diagnosis,gene function,chromatography ,electrophoresis, Quantitative techniques,crystallography,Bioinformatics analysis..