New Developments and Advancements in Mass Spectrometry

Mass spectrometry is an analytical technique used to determine known materials and to identify unknown compounds within a given sample and to explain the structure and chemical properties. The technique involves in studying the effect of ionizing energy on molecules. It also depends upon chemical reactions in the gas phase in which sample molecules are consumed during the formation of ions. The three major components are Ion Source, Analyzer, Detector System.

Analysis of Biomolecules using Mass Spectrometry, Analysis of Glycans, Lipids, Proteins and Peptides, Oligonucleotides, Data Analysis, Membrane Protein Analysis etc.,

Mass Spectrometry has multiple use in techniques like Matrix Assisted Laser Desorption-Ionization, Electrospray Ionization, Protein Topology, Labelling Techniques, Mass analyzer designs.

Advancements:

The technique of using mass spectrometry is called laser induced liquid bead ion desorption which in terms referred as (LILBID). This technique allows us to detect membranes proteins by developing a series of microdroplets and then get radiated using a laser of an IR range. These can be identified at lower intensities complexes whereas in higher intensities subunits can be known. This new technique can also be thought as combination of another type of MS often used MALDI and electrospray. In addition, the studies using this ES technique shows that micelles can certainly exist in the gas phase.

Mass spectrometry in the logical strategy and being further used in labs by Scientists and Researcher from   past  25years.

Protein Analysis

Raman Microscopy

Magnet sector microscopy

Hyper Reaction Monitoring