Mass Spectrometry in Pharmaceutical Industry

Mass spectrometry (MS) is an analytical tool with many applications in pharmaceutical and biomedical field. The increase in sensitivity and resolution of the instruments has increased the analysis of pharmaceuticals, complex metabolites of biological systems. The accuracy in detecting the molecular weight of compounds by using the MS and through which we can anticipate the molecular formulas. Biochemical applications of mass spectrometry (MS) are important in the pharmaceutical industry. MS techniques have been well adapted and are now the preferred choice for many applications in pharmaceutical development. MS technology has evolved as emerging tool for many applications in drug development and Discoveries.

Stages Drug Development:

Drug discovery

Pre-Clinical Development

Clinical development

Manufacture

Mass Spectrometry is more considered as the most sensitive detector which is typically coupled with other technologies such as High-Performance Liquid Chromatography (HPLC), Ion Chromatography (IC), Ion Mobility Spectrometry (IMS), Gas Chromatography (GC) etc., these techniques are more used in drug development due to their speed, sensitivity and selectivity.