Mass Spectrometry Applications in Clinical Diagnostics
Mass Spectrometry is an analytic technique having high accuracy and growing use in laboratory medicine. MS technology in clinical laboratories is used for monitoring of drug therapy, identifying drug toxicity, Disease screening, diagnosis of disease and metabolic disorders, poisoning and discover of new biomarkers. The combination of MS with Liquid Chromatography (LC-MS), Matrix-Assisted Laser Desorption/Ionization (MALDI), Gas Chromatography (GC-MS) and Time-Of-Flight (TOF MS). Mass Spectrometry has overcome the issues associated with immunoassays. The test carried in clinical laboratory using Mass Spectrometry will become routine diagnostic tools in the clinical laboratories and there is a vast usage of Mass Spectrometry and the brief discussion ends with new development methods in clinical diagnostics.